Medical digital twins are computational models of human biology relevant to a given medical condition, which can be tailored to an individual patient, thereby predicting the course of disease and individualized treatments, an important goal of personalized medicine. Since the immune system is a key factor in many diseases, it demands special attention. In February 2023, an international group of experts convened in Lake Nona, FL, for two days to discuss problems related to digital twins of the immune system. The group consisted of clinicians, immunologists, biologists, and mathematical modelers, representative of the interdisciplinary nature of medical digital twin development. Video recordings of all presentations (titles are hyperlinks) and a downloadable meeting report are available at https://systemsmedicine.pulmonary.medicine.ufl.edu/working-groups/forum-on-precision-immunology-immune-digital-twins/. 

Posted on behalf of Reinhard C. Laubenbacher, Ph.D. University of Florida